This whitepaper maps out a standards-aligned, simulation-first workflow for validating Level3–4 driver-assist and autonomous functions. It builds on ISO21448(SOTIF) hazard analysis, PEGASUS’s six-layer scenario taxonomy and ASAMOpenX formats, showing how MORAISIM and ScenarioRunner execute cloud-scale batches that replay EuroNCAP, UNR157, DDT-failure and ODD-exit scenarios . Readers will learn how reusable scenario databases, coverage metrics and traceable evidence accelerate certification, surface hidden edge cases and reduce costly real-world mileage